Order Griseofulvina (Griseofulvin) tablets online in the USA

| Product Name | Griseofulvin (Griseofulvina) |
| Dosage | 125 mg, 250 mg, 500 mg (microsize or ultramicrosize formulations) |
| Active Ingredient | Griseofulvin (Griseofulvina) |
| Form | Oral Tablets |
| Description | Systemic antifungal used for dermatophyte infections of skin, hair, and nails (ringworm). Not active against Candida or tinea versicolor. U.S. prescription required; online clinician review available. |
| How to Order Without Prescription | Online pharmacy with U.S. telehealth evaluation when appropriate |
Griseofulvin (often referred to internationally as Griseofulvina) is a long-standing antifungal medication in the United States that treats ringworm and other dermatophyte infections affecting the skin, scalp, hair, and nails. Unlike topical antifungals that work on the surface, griseofulvin acts systemically and concentrates in keratin precursor cells, helping protect newly formed skin, hair, and nail tissue from fungal invasion while infected tissue grows out. In the U.S., griseofulvin is available in oral tablet formulations, commonly in 125 mg, 250 mg, and 500 mg strengths, with dosing that differs between microsize and ultramicrosize products. While this medicine is prescription-only, our partner pharmacy can facilitate a streamlined U.S. telehealth review so eligible adults can receive appropriate treatment conveniently and quickly, with discreet delivery nationwide.
This antifungal is marketed under several brand and generic names and remains an important option, particularly for tinea capitis (scalp ringworm) in children and certain stubborn dermatophyte infections in adults. Because it is fungistatic rather than fungicidal, griseofulvin is typically taken for several weeks to months depending on the site of infection, with the goal of allowing healthy keratin to replace infected tissue. In the USA, clinicians may consider other systemic antifungals (such as terbinafine or itraconazole) for some conditions, but griseofulvin continues to be a clinically valuable choice, especially when specific pathogens or patient factors favor its use. Our trusted U.S. partner network supplies FDA-approved medications and provides support so patients can order griseofulvin with appropriate clinical oversight, clear instructions, and timely delivery.
Griseofulvin price and availability in the USA
Griseofulvin is widely available in generic formulations throughout the United States, which helps keep costs competitive. Actual pricing can vary by dosage strength, formulation (microsize versus ultramicrosize), and package size, as well as by pharmacy location and insurance coverage. As a general reference, many U.S. pharmacies stock 250 mg tablets in bottles or blister-style packs, and cost per tablet tends to decline when ordering larger quantities. Through our partner pharmacy, customers can view current pricing in real time, apply available promotions, and opt for tracked shipping to any U.S. address. Because griseofulvin requires a prescription in the United States, orders are reviewed by a licensed clinician when using our online telehealth flow; if approved, the medication is dispensed and shipped quickly.
For example, a smaller 125 mg strength may be chosen for weight-based pediatric dosing in tinea capitis, while adults often use 250 mg or 500 mg strengths based on the formulation and clinical plan. To improve affordability, our partner pharmacy offers value packs and periodic discounts, and many patients find that the effective per-tablet cost is substantially lower with larger refills when medically appropriate. Patients should remember that total treatment cost also depends on the necessary duration of therapy, which can range from several weeks (for skin infections) to multiple months (for nail infections), and that adherence is critical for successful outcomes and to prevent recurrence.
Because prices and availability may change, we encourage checking the current U.S. pharmacy listings and completing a quick online intake so a licensed provider can confirm whether griseofulvin is an appropriate option for your diagnosis and health profile. Where another systemic antifungal could be more suitable, a clinician may recommend alternatives to achieve optimal efficacy, tolerability, and duration.
Where can I buy Griseofulvin in the USA?
In the United States, griseofulvin is a prescription medicine. If you’ve been diagnosed with a dermatophyte infection (for example, tinea capitis, tinea corporis, or onychomycosis) and your clinician recommends griseofulvin, you can purchase it through our partner pharmacy with convenient nationwide shipping. If you do not yet have a prescription, our U.S.-based telehealth service can evaluate your case online; when clinically appropriate, a licensed prescriber may issue a prescription that is forwarded directly to the dispensing pharmacy. This process makes it easier to receive guideline-based care from home while maintaining regulatory and safety standards.
Our platform has served millions of customers in North America and globally by combining secure ordering, transparent pricing, and pharmacist-led support. Whether you are managing a new scalp infection in a child, addressing persistent ringworm on the body, or beginning a longer course for nail involvement, our team is committed to streamlining access to the right antifungal therapy and providing clear educational materials on how to use it correctly.
For individuals who prefer not to make in-person appointments or who need rapid access to treatment, the online pathway is especially helpful. You’ll receive practical guidance about dosing differences between microsize and ultramicrosize tablets, tips for taking griseofulvin with fatty meals to enhance absorption, and information on follow-up and monitoring. Our credentialed pharmacists are available to answer questions about interactions, precautions, and what to expect during therapy so you can feel confident throughout your treatment course.
Griseofulvin in the U.S. healthcare setting
In American clinical practice, griseofulvin holds a well-defined role for dermatophyte infections, particularly tinea capitis, where it has historically been a first-line therapy and remains widely used. While alternatives like terbinafine may be preferred for certain species or nail disease, griseofulvin’s long track record, pediatric familiarity, and keratin-targeting mechanism make it a dependable choice in many scenarios. If you or your child are starting griseofulvin, your clinician will consider factors such as age, weight, infection site, organism, past response to therapy, and potential drug interactions to determine the correct formulation and duration.
What is Griseofulvin?
Griseofulvin (Griseofulvina) is an oral antifungal medication derived from Penicillium species that is used to treat infections caused by dermatophytes—fungi that invade keratinized tissues such as the outer skin, hair, and nails. It is not effective against Candida (yeast) infections or tinea versicolor (caused by Malassezia). Griseofulvin’s mechanism is primarily fungistatic: it disrupts fungal microtubules and interferes with mitosis, while binding to keratin in host tissues so that newly formed keratin is resistant to fungal invasion. Over time, infected tissues are shed and replaced by healthy tissue protected by the drug, leading to clinical cure when taken for the prescribed duration.
Griseofulvin is available as microsize and ultramicrosize tablets. These formulations are not interchangeable on a milligram-for-milligram basis because ultramicrosize products have higher bioavailability. As a result, typical doses differ between the two forms. To maximize absorption, griseofulvin should be taken with a fatty meal or with milk. Adherence to daily dosing and completing the full course are critical to minimize relapse and reduce the need for retreatment.
Because dermatophyte infections often affect household contacts or are spread in community settings (for example, among children in schools or athletes sharing equipment), clinicians may also recommend non-pharmacologic measures—such as not sharing hairbrushes or hats, disinfecting surfaces and combs, and treating concomitant tinea infections elsewhere on the body—to prevent reinfection.
Griseofulvin for tinea capitis (scalp ringworm)
Tinea capitis is a common fungal infection of the scalp and hair shafts, especially in children. It can present with scaly patches, hair loss, broken hairs (black dots), and, in inflammatory forms, tender boggy plaques (kerion). Topical therapy alone is insufficient, as it does not adequately penetrate hair follicles. Griseofulvin has been a cornerstone for tinea capitis management because it concentrates in hair keratin and is generally well tolerated when dosed by weight. Depending on the infecting species, an alternative like terbinafine may be recommended by some clinicians; however, griseofulvin remains a reliable, frequently used option, particularly for Microsporum species where it may be preferred.
During treatment, clinicians often advise using adjunctive antifungal shampoos (such as selenium sulfide or ketoconazole) two to three times per week to reduce spore counts and potentially decrease transmission. Combs, hats, and pillowcases should be cleaned regularly, and close contacts who share hair-care items may need evaluation. In inflammatory tinea capitis with kerion formation, your clinician may consider additional measures to reduce swelling and discomfort. Early diagnosis and adherence to a full course of therapy are important to lower the risk of scarring alopecia.
Because school and sports participation can influence spread, practical infection-control steps—avoiding sharing personal items, routine laundering of linens, and adherence to treatment—can help children return to normal activities quickly and safely. Your healthcare provider will also advise on when it’s appropriate to resume communal activities.
Why griseofulvin remains important for scalp infections
Griseofulvin’s selective action against dermatophytes and deposition in keratinizing tissues make it uniquely suited for scalp disease, where hair follicle involvement is difficult to reach with topical agents. Its decades of pediatric use have clarified weight-based dosing, safety monitoring, and common side effects. Even as newer antifungals have become available, griseofulvin often remains a first or second choice for tinea capitis, depending on the fungal species and local epidemiology. Parents and caregivers appreciate its oral dosing, and clinicians value its established efficacy and safety profile when used carefully under medical supervision.
Griseofulvin for onychomycosis and skin ringworm
Griseofulvin can be prescribed for tinea unguium (onychomycosis) and for ringworm of the body, groin, or feet when systemic therapy is indicated. Nail infections generally require the longest courses—often several months—because nails grow slowly and the drug must protect newly forming nail keratin as the diseased portion grows out. For tinea corporis (body ringworm) and tinea cruris (jock itch), clinicians may start with topical agents, but switch to systemic therapy like griseofulvin if the infection is widespread, recalcitrant, or involves hair-bearing areas. For tinea pedis (athlete’s foot), systemic therapy may be considered for moccasin-type or extensive involvement, or when topical treatment repeatedly fails.
In the United States, a clinician may weigh the relative benefits of terbinafine versus griseofulvin for nail disease. Terbinafine is often favored for toenails due to shorter courses and higher cure rates for many Trichophyton infections, yet griseofulvin can be a reasonable alternative in certain patients based on tolerability, contraindications to alternatives, or specific organism susceptibility. Whichever option is chosen, confirming the diagnosis (e.g., by KOH microscopy, culture, or PCR) can improve treatment success by ensuring that a dermatophyte is present and help avoid unnecessary exposure to systemic antifungals for non-fungal nail dystrophies.
Mechanism of action
Griseofulvin binds to fungal microtubules and disrupts the mitotic spindle, inhibiting fungal cell division. Additionally, it integrates into keratin precursor cells in host tissues; as a result, the new keratin that forms while taking griseofulvin is resistant to dermatophyte invasion. Because the drug protects newly formed tissue while infected tissue is gradually shed, it is essential to continue therapy for the full recommended duration, even if symptoms begin to clear earlier. This approach ensures that enough healthy, fungus-resistant keratin replaces infected material to achieve a durable clinical cure.
Safety profile
Griseofulvin has been used for decades and is generally well tolerated when prescribed and monitored appropriately. Common side effects include headache, gastrointestinal upset (nausea, diarrhea, abdominal discomfort), fatigue, and mild skin reactions such as rash or urticaria. Photosensitivity can occur, so patients are advised to use sun protection. Rare but serious adverse effects may include hepatotoxicity, severe skin reactions (e.g., Stevens–Johnson syndrome), hematologic changes (e.g., leukopenia), or proteinuria. As with any systemic medication, patients should promptly report concerning symptoms to their clinician and follow recommended lab monitoring if advised, especially for longer courses or in the presence of liver comorbidities.
Griseofulvin dosing for adults and children
Griseofulvin dosing depends on the formulation: microsize products typically require higher milligram doses than ultramicrosize products due to differences in bioavailability. For tinea capitis in children, weight-based dosing is commonly used and courses typically extend 6–12 weeks or until two weeks after symptom resolution, depending on clinical response and pathogen. Adults may take daily doses based on the site and severity of infection, with durations ranging from a few weeks for skin disease to several months for nail involvement. Because correct dosing and duration are important for success, always follow your prescriber’s directions and do not stop early unless instructed.
To improve absorption, take griseofulvin with a fatty meal or milk. If you miss a dose, take it when remembered unless it is near the time for your next dose, in which case skip the missed dose and resume your regular schedule. Do not double up doses. Consistency is key: taking the medication at the same time each day can help maintain effective tissue levels.
Using griseofulvin during pregnancy and breastfeeding
Griseofulvin is generally not recommended during pregnancy due to potential risks, and women who could become pregnant should use reliable contraception while taking this medicine. There is also concern about reduced effectiveness of combined oral contraceptives when coadministered with griseofulvin; additional non-hormonal birth control is advised during therapy. Men may be counseled to use effective contraception during treatment and for a period after completion because of potential effects on sperm. If you are nursing or planning to breastfeed, consult your clinician to weigh potential risks and benefits and explore alternative antifungal options when appropriate.
Strongyloidiasis
Griseofulvin is not used for strongyloidiasis. This section is included to clarify that, unlike antiparasitic drugs, griseofulvin treats dermatophyte fungal infections and is not indicated for parasitic diseases such as strongyloidiasis. If you suspect a parasitic infection, consult a healthcare professional to obtain the right diagnosis and treatment, as therapies, dosing, and safety profiles differ substantially from antifungal medications.
Onchocerciasis
Onchocerciasis (river blindness) is also not an indication for griseofulvin therapy. This antifungal is specifically targeted to dermatophyte fungi in keratinized tissues and does not have clinical utility for filarial or other parasitic infections. Patients with potential exposure to onchocerciasis or compatible symptoms should seek evaluation by a clinician who can recommend appropriate antiparasitic regimens and follow-up.
How to take griseofulvin correctly
Follow your clinician’s instructions carefully. In general, griseofulvin should be taken with food—ideally a meal that contains fat—to improve absorption. Take it at the same time each day and complete the entire course, even if your skin looks clearer or symptoms have improved. For scalp infections, your clinician may suggest using antifungal shampoos two to three times per week in addition to oral therapy, which helps reduce surface fungal load and the risk of transmission. For nail infections, keep nails trimmed and dry, and follow guidance on foot hygiene and shoe care to support the medication’s effect.
If your clinician orders lab tests (for example, to check liver function during prolonged therapy), complete them as scheduled. Contact your healthcare provider if you develop unusual symptoms, if your rash worsens, or if you notice any signs of liver problems such as dark urine, jaundice, or persistent nausea and fatigue. Do not share your medication with others and do not use leftover tablets for new episodes without medical advice.
To reduce reinfection risk, avoid sharing towels, hats, combs, or hair accessories. Clean or replace hairbrushes and combs periodically during therapy, and consider treating pet exposures if a veterinarian suspects zoonotic transmission. Small household steps like laundering pillowcases and gym clothing frequently can support recovery and reduce the chance of recurrence.
Safety precautions
Do not take griseofulvin if you are allergic to it or to any component in the formulation. Use caution and consult your clinician if you have a history of liver disease, systemic lupus erythematosus, or porphyria. Avoid excessive sun exposure and use sunscreen due to the risk of photosensitivity. Because griseofulvin may reduce the effectiveness of hormonal contraceptives, use additional or alternative birth control while taking it and for the time recommended by your clinician. Alcohol may increase the risk of adverse reactions in some individuals; minimizing alcohol intake while on therapy is prudent.
If you are on long-term therapy (for example, for nail infections), your prescriber may recommend periodic laboratory monitoring. Report any severe skin reactions, persistent headaches, unusual fatigue, bruising, or signs of infection. As with all prescription medicines, keep griseofulvin out of reach of children and store it according to the pharmacy label, typically at room temperature away from moisture and heat.
People with extensive dermatophyte infections or those who are immunocompromised may require individualized plans. Your clinician may adjust dose or duration, switch to an alternative antifungal, or use combination approaches. Always provide a full medication list during consultations so your care team can mitigate interaction risks.
Griseofulvin side effects
Most people tolerate griseofulvin well. Common side effects tend to be mild and temporary and can include headache, nausea, vomiting, diarrhea, dizziness, fatigue, and transient rash or hives. Photosensitivity reactions may occur, so sun protection is recommended. Rare but more serious reactions could involve liver inflammation, significant skin eruptions (up to and including severe reactions), hematologic changes such as leukopenia, or renal findings like proteinuria. Seek immediate medical care for symptoms of a serious allergic reaction, such as sudden rash, swelling of the face or throat, severe dizziness, or breathing difficulties.
Adverse effects can vary with treatment duration and patient factors. People on longer courses—such as those treating onychomycosis—should stay alert to persistent or unusual symptoms and engage in recommended monitoring. Your pharmacist or prescriber can also advise on supportive measures to mitigate common side effects, such as taking the medication with food and adequate hydration.
As with other systemic antifungals, early communication with your clinician about new symptoms is key to safe and effective therapy. Do not discontinue or adjust your dose without guidance, as erratic dosing can reduce efficacy and encourage recurrence.
Symptoms by infection type
For dermatophyte infections treated with griseofulvin, you may notice the following during therapy: for tinea capitis, initial shedding of broken hairs and scalp scale may gradually give way to healthier growth as the medication protects new hair keratin; for body ringworm, spreading margins and scaling should recede with time; and for nail disease, the discolored, thickened areas should progressively grow out as new nail forms. Mild itching or dryness can persist early on while damaged tissue resolves. If your condition worsens or fails to improve after the expected timeframe, contact your clinician to reassess the diagnosis and management plan.
- unusual weakness
- loss of appetite, abdominal pain, constipation or diarrhea
- nausea or vomiting
- drowsiness or dizziness
- anxiety
- decreased white blood cell count
- anemia (reduced red blood cells)
Because griseofulvin is not used for lymphatic filariasis or parasitic diseases, the symptom profile for those conditions does not apply here. If you have systemic symptoms such as high fever, respiratory difficulties, or unexplained swelling that are not typical of dermatophyte infections, seek medical attention to evaluate for other causes and appropriate therapies.
- sweating or fever
- headache
- unusual weakness
- muscle and joint pain or body aches
- loss of appetite, nausea
- upper or lower abdominal pain
- cough or sore throat
- shortness of breath
- low blood pressure
- fainting or dizziness when standing
- chills
- dizziness
In patients with scalp ringworm under treatment, mild scalp irritation or itching can occur as fungal debris clears and hair regrowth begins. This usually improves with continued therapy and adjunctive scalp hygiene. If an inflammatory kerion is present, your clinician will provide specific instructions, including when to seek in-person evaluation for complications or scarring risk.
- itching that may initially persist or fluctuate as damaged skin or hair clears; report any rapidly worsening or severe symptoms
For those being treated for nail disease, be aware that nails grow slowly and cosmetic improvement is gradual. Distal clearing with a healthy growth line can be a positive sign, but it may take many months to fully replace diseased nail. Your clinician will advise on the expected timeline and strategies to reduce reinfection such as foot care, shoe hygiene, and managing comorbid tinea pedis.
- itching or rash
- joint or muscle pain
- fever
- nausea or vomiting
- inflamed lymph nodes
- swelling of hands, ankles, or feet
- diarrhea
- dizziness
- low blood pressure
- fainting when standing
- rapid heartbeat
- headache or fatigue
- vision problems such as eye irritation or redness should prompt evaluation, especially if persistent, and may indicate unrelated conditions
Reporting side effects
If you experience side effects while taking griseofulvin, contact your healthcare provider or pharmacist. Seek immediate medical attention if you develop signs of a serious allergic reaction or severe skin reaction. You can also report adverse events to the FDA’s MedWatch program. Prompt reporting helps your care team optimize your therapy and supports community safety surveillance.
Interaction of griseofulvin with other medicines
Griseofulvin can interact with certain medications and supplements. Always provide a full list of your prescription and over-the-counter medicines, vitamins, and herbal products to your clinician and pharmacist. Notable interactions include reduced efficacy of warfarin (necessitating closer INR monitoring and possible dose adjustment) and decreased effectiveness of hormonal contraceptives (use additional non-hormonal birth control during therapy). Enzyme inducers such as barbiturates may lower griseofulvin levels and reduce antifungal efficacy. Alcohol may potentiate adverse reactions in some people. Your prescriber will evaluate risks and tailor your plan accordingly.
Some medicines that may interact with griseofulvin include:
- barbiturates (e.g., phenobarbital, butalbital)
- benzodiazepines (e.g., clonazepam, lorazepam)
- sodium oxybate (GHB)
- valproic acid
- warfarin
This list is not exhaustive. Provide a complete medication and supplement list during your consultation so your clinician can monitor for interactions, make dose adjustments when needed, and recommend safe timing or alternatives.
Recommendations from our specialists
If you or a family member has been diagnosed with a dermatophyte infection such as tinea capitis, ringworm of the body, or nail fungus, griseofulvin may be an appropriate option depending on species, site, and patient-specific factors. Because U.S. regulations require a prescription, our experts recommend using our streamlined telehealth intake to obtain a clinician review. When griseofulvin is prescribed, take each dose with a fatty meal to improve absorption, adhere closely to the therapy schedule, and follow adjunctive hygiene steps to limit reinfection. If another antifungal is more suitable based on your infection or medical history, our clinicians will recommend the best alternative and arrange dispensing through our partner pharmacy with fast U.S. delivery.
Ready to treat ringworm effectively? Order Griseofulvin today
Skip the hassle of in-person visits and get rapid access to FDA-approved antifungal therapy with licensed U.S. clinician oversight. Our partner pharmacy offers secure checkout, discreet packaging, and nationwide shipping, backed by responsive pharmacist support to ensure you use your medication safely and effectively.
- Prescription support — quick online clinical review with U.S.-licensed providers
- Fast, secure shipping across the United States, with tracking
- Genuine medication dispensed by accredited U.S. pharmacies
- Competitive pricing on multiple strengths and formulations
- Expert guidance on dosing, interactions, and prevention of reinfection
Join patients nationwide who trust our network for convenient, reliable antifungal care. Begin your griseofulvin therapy today and take the next step toward clear skin, healthy hair, and stronger nails with physician-directed treatment you can start from home.
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